ea0037ep693 | Pituitary: basic and neuroendocrinology | ECE2015
Rotondi Sandra
, Modarelli Alessio
, Sanita Patrizia
, Angelucci Adriano
, Jaffrain-Rea Marie-Lise
We have recently observed that the peroxisome proliferator receptor α was expressed by normal and tumoural pituitary tissues, in particular by somatotrophs. To elucidate its function, we have studied the effects of fenofibrate on cell proliferation and GH secretion in GH3 cells.Material and methods: GH3 cells were grown in Hams F10 and treated for 24, 48 and 72 h by different concentrations of fenofibrate (12.550 &#...